THE ROLE OF INTRAVITREAL BEVACIZUMAB ON CYSTOID MACULAR EDEMA

Authors

  • Bakhtiar Qadir Hamasalh Department of Surgery, Ophthalmology College of Medicine, University of Sulaimani, Kurdistan Region, Iraq.
  • Tablo Ahmed Mirza Shaheed Dr. Aso Teaching Eye Hospital, Sulaimani, Kurdistan Region, Iraq.
  • Fazil Ahmad Abdulla Department of Community Medicine, College of Medicine, University of Sulaimani, Kurdistan Region, Iraq.

DOI:

https://doi.org/10.17656/jsmc.10302

Keywords:

Intravitreal, Bevacizumab, Diabetic retinopathy, Avastin

Abstract

Background 

Cystoid macular edema (CME) is an intracellular accumulation of fluid in the retinal layers around the fovea; it contributes to reducing visual acuity by altering the functional cell relationship in the retina.

Objectives 

To detect the role of intravitreal Bevacizumab (Avastin) on decreasing central retinal thickness in patients with cystoid macular edema. 

Materials and Methods

In a prospective study in Shaheed Dr. Aso Eye Hospital in As-Suleimanyah city, 65 patients with macular edema by Ocular coherent tomography (OCT) included, after a single intravitreal avastin injection, we repeated the OCT after 2 weeks & 3 months after the injection.

Results

Central retinal thickness was greatly decreased in Diabetic patients and CRVO during the follow-up period, but a lesser effect was seen in BRVO. The immediate response was seen in ARMD after 2 weeks. Central retinal thickness decreased more in those patients who received Avastin alone than patients treated by Avastin with Laser photocoagulation. There was no significant improvement of visual acuity in the patients after IVTA injection 

Conclusion

Avastin is an effective drug in decreasing central retinal thickness and delaying its complications mostly in patients with Diabetic retinopathy and CRVO, and reduces the need for LASER therapy in these patients.

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Published

2021-06-21

How to Cite

1.
Hamasalh B, Mirza T, Abdulla F. THE ROLE OF INTRAVITREAL BEVACIZUMAB ON CYSTOID MACULAR EDEMA. JSMC [Internet]. 2021 Jun. 21 [cited 2024 Jul. 20];11(2):189-94. Available from: https://jsmc.univsul.edu.iq/index.php/jsmc/article/view/jsmc-10302

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