COMPARING CORONARY ANGIOGRAPHIC FINDINGS AMONG DIABETIC AND NON-DIABETIC PATIENTS

Authors

  • Taha Othman Mahwi Department of Medicine, College of Medicine, University of Sulaimani, Kurdistan Region, Iraq.
  • Aram Jamal Mirza Cardiology Consultant, Sulaimani Directorate of Health, Kurdistan Region, Iraq.
  • Redwan Jaza Abdalwahid Internal Medicine Board Trainee, Sulaimani, Kurdistan Region, Iraq.

DOI:

https://doi.org/10.17656/jsmc.10200

Keywords:

Coronary angiography, Diabetes mellitus, Coronary artery disease

Abstract

Background 

Diabetes mellitus is worldwide metabolic and vascular problem characterized by hyperglycemia. People with diabetes have a 4-fold-greater risk for having a cardiovascular disease than people without diabetes.

Objectives 

To look at the effect of diabetes mellitus on the number of the coronary vessels involved and the extent of coronary artery disease and the association of different socio-demographic characteristics in respect to diabetic and non-diabetic patients.

Patients and Methods

A cross-sectional observational study was conducted on two hundred patients who were admitted to Sulaimani Cardiac Teaching Hospital between March and September 2018. Half of the cases were diabetic and the other half were non-diabetic.

Results

Among the total of 200 patients involved in the study, 59% were males and 41% were females. Mean age was 60.98±10.60. Average HbA1c% value for DM patients was 8.46±2.10. Coronary angiography results in diabetic patients were positive for more multi vessel disease than non-diabetic patients (53% vs. 39%) (p value = 0.005). Diabetic patients were more likely to be hypertensive than non-diabetic patients (59% vs. 40%) (p value=0.001).

Conclusion

Diabetes mellitus is a risk factor for coronary artery disease and diabetic patients had more extensive CAD, which is comparable to other studies done in different countries.

References

Salim M. AL-rubae . Evaluating coronary artery disease in type 2 diabetes mellitus and other risk factors by angiographic study. World J Cardiology;2015 March 26;119-124.

Diabetes related Micro and Macrovascular Diseases in the Physical Therapy Setting.2008 Nov;88(11):1322-35. DOI: https://doi.org/10.2522/ptj.20080008

Salim Yusuf, DPhil. Srinath Reddy, MD. Sonia Anand; Global burden of cardiovascular diseases part 1. General considerations, the epidemiologic transition, risk factors and impact of urbanization. Circulation 2001 Nov 27; 104(22)2746-53. DOI: https://doi.org/10.1161/hc4601.099487

M K Malthesh , T M Mohammed Sakib, P Mallesh . Coronary artery involvement in diabetic and non-diabetic patients with acute coronary syndrome. Internal Journal of Scientific Study;March 2016 ; Vol 3 ; Issue 12.

Baim DS, Grossman W. Coronary angiography in Grossman’s cardiac catheterization. Angiography and interventions.6th edition; Lippincott Williams & Wilkins; 2000; p 211-213.

ACC/AHA Blood Pressure Guidelines.2017 June 1st .

Krone RJ, Shaw RE , Klein LW, Block PC. Evaluation of American College of Cardiology / American Heart Association and the society for coronary angiography and Interventions lesion classification system in the current stent era of coronary intervention. American Journal of Cardiology 2003.92;389-94. DOI: https://doi.org/10.1016/S0002-9149(03)00655-6

M K Malthesh , T M Mohammed Sakib, P Mallesh. Coronary artery involvement in diabetic and non-diabetic patients with acute coronary syndrome. International Journal of Scientific Study ; March 2016 ; Vol 3 ; Issue 12.

Andreini D , Prontone G, Bartorelli A, Agostoni P, Mushtaq S. Comparison of the coronary angiography in diabetic and non-diabetic patients with coronary artery disease. Cardiovascular and Diabetology.2010; 9:80. DOI: https://doi.org/10.1186/1475-2840-9-80

Dubey L, Guruprasad S, Subramanyam G, Relationship between type 2 diabetes mellitus and coronary artery lesion characteristics. a single center study. Nepalese heart journal.2013; 10(1);20-22. DOI: https://doi.org/10.3126/njh.v10i1.9742

Kadhim AR, Strak SK, Hazaa MA. Coronary angiographic findings in diabetic and non-diabetics with coronary heart disease.Al-Kindy College of Medicine Journal 2013;9(1):23-30.

Mudhafar Abdulrahman Albarzani. Angiographic profile in diabetic and non-diabetic patients with coronary artery disease in the Cardiac Specialty Hospital – Cardiac Center, Erbil, Ira.Zanko Journal of Medicine; August 2017 ; Vol.21;No.2. DOI: https://doi.org/10.15218/zjms.2017.023

Shah BS, Deshpande SS. Assessment of demographics, treatment strategies and evidence based medicine use among diabetic and non-diabetic patients with acute coronary syndrome. Journal of pharmacology 2014 ;5(2);139-144. DOI: https://doi.org/10.4103/0976-500X.130058

Tanjima parvin, MD abu Siddique , Smahsan Habib. Angiographic severity of coronary artery disease in diabetic and non-diabetic patients in a tertiary care centre. University Heart Journal ;January 2014; vol.10;No.1. DOI: https://doi.org/10.3329/uhj.v10i1.24590

Muataz FH. Clinical and angiographic findings in diabetic vs. non-diabetic Iraqi patients with ischemic heart disease. Iraqi Postgraduate Journal 2011; 10(3): 339-346.

Alka M. Kanaya.Explaining sex Difference in Coronary Heart Disease Mortality among Patients with Type 2 Diabetes Mellitus.August 2002 August 12. Archives of Internal Medicine 162(15):1737-45. DOI: https://doi.org/10.1001/archinte.162.15.1737

Hadamitzky M, Hein F, Meyer T. Prognostic value of coronary computed tomographic angiography in diabetic patients without known coronary artery disease. Diabetes Care 2010.33(6);1358-63. DOI: https://doi.org/10.2337/dc09-2104

Krul MM, Baggard K, Kno RJ, Rossum AC. Coronary artery disease in patients with a typical chest pain and without diabetes mellitus assessed with coronary CT angiography.BMJ open Diabetes Research and Care 2014;2:1-9. DOI: https://doi.org/10.1136/bmjdrc-2013-000004

Jamee A, Abed Y, Ramadan M, El-Rabia K. Impact of diabetes mellitus on coronary artery disease in women attending coronary angiography in Gaza-Palestine.An observational study. Cardiology and Angiology 2015;4(1):10-18. DOI: https://doi.org/10.9734/CA/2015/17940

Mahalie N, Grag MK, Naik SS. Association of metabolic syndrome with severity of coronary artery disease.Indian Journal of Endocrinology and Metabolism.2014:18(5):708-14. DOI: https://doi.org/10.4103/2230-8210.139238

Rezende PC, Rahimi RM, Uchido AH, Costa LM. Type 2 diabetes mellitus and myocardial ischemic preconditioning in symptomatic coronary artery disease patients.Cardiovascular and Diabetology 2015 May 30; 14:66. DOI: https://doi.org/10.1186/s12933-015-0228-x

Mohammad HN. Cardiovascular disease and risk factors among diabetic patients in Nablus district.West bank, Palestine : Case – control study . MSc thesis. Palestine 2014:1041-9 ·

Natalia A, Vichi S, Landi P, Severi S. Coronary atherosclerosis in type 2 diabetes : angiographic findings and clinical outcome. Diabetologia 2000;43(5):632-41. DOI: https://doi.org/10.1007/s001250051352

Effect of BMI on Outcome In Patients with Suspected Coronary Artery Disease Referred for Stress Echocardiography.American Journal of Cardiology.2013 Nov.1st ;Volume 112 ;Issue 9;1355-60. DOI: https://doi.org/10.1016/j.amjcard.2013.06.024

FOX CS, Sultan L, Wilson PW, Framingham heart study. The significant effect of diabetes duration on coronary heart disease mortality, the Framingham heart study. Diabetes Care. Framingham Heart Study. Diabetes Care.2004;2793;704-706. DOI: https://doi.org/10.2337/diacare.27.3.704

SRINIDHI S.HEGDE, P.MALLESH , S.M. YELI . Comparative angiographic profile in diabetic and non-diabetic patients with acute coronary syndrome.US National Library of Medicine; 2014 September 21;Vol.8; MC07–MC10. DOI: https://doi.org/10.7860/JCDR/2014/9072.4851

Saleem T, Mohammad KH. Association of glycosylated hemoglobin level and diabetes mellitus duration with the severity of coronary artery disease. Diabetes and Vascular Research.2008;5(3);184-89. DOI: https://doi.org/10.3132/dvdr.2008.030

British Medical Journal; 2000 August;405-412 . DOI: https://doi.org/10.1038/35013187

Jose A. Silva, Alvaro Escovar, Tyrone J. Collins. A comparison of angiographic findings between diabetic and non-diabetic patients. Journal of American Heart Association.1995;92:1731-1736. DOI: https://doi.org/10.1161/01.CIR.92.7.1731

Waller B, Palumbo P, Roberts W. Status of the coronary arteries at necropsy in diabetes mellitus with onset after age 30 years.American Journal of Medicine.1980;69;498-506. DOI: https://doi.org/10.1016/S0149-2918(05)80002-5

Afsar MN, Ahmed K , Rahman S. A comparative study of coronary angiographic findings between diabetic and non-diabetic patients. Journal of Clinical and Diagnostic Research 2014 Sep; 8 (9): MC07–MC10.

Krishnaswami S, Joseph G, Chandy ST. Coronary angiographic findings in patients with diabetes : an exercise in cardiovascular epidemiology.Journal of Association of Physicians of India 1996;44(3);169-71.

Jose Marconi, Almeida de Sousa, Marco Teodoro. Comparison of coronary angiography findings in diabetic and non-diabetic women with non-ST segment elevation acute coronary syndrome. Arquivos Brasileiros de Cardiologia ; March 2006; 86(2):150-5

Hoque MH, Sufia R, Siddique Ma, Zaman SMM, Mahmood M. Coronary stenting in diabetic patients : evaluation of immediate prodcedural success and adverse outcomes.Unibrtsity Heart Journal .2010;6(1):3-8. DOI: https://doi.org/10.3329/uhj.v6i1.7181

Mossavi M, Nematipour E, Mehrpooya M. Comparison of extent of coronary artery disease in angiography of diabetics and non-diabetics.Iran Heart Journal 2006;7;37-42.

Uddin SN, Malik F, Bari MA, Khan GK , Rahman S . Angiographic severity and extent of coronary artery in patients with type 2 diabetes mellitus .Mymensingh Medical Journal 2005;14:32-37.

Nicholls SJ, Tuzcu EM, Kalidindi S, Moon KW. Effects of diabetes on progression of coronary atherosclerosis and arterial remodeling . A pooled analysis of 5 intravascular trials. Journal of American College of Cardiology.2008;52:255-262. DOI: https://doi.org/10.1016/j.jacc.2008.03.051

Rana JS, Dunning A, Al-Mallah M. Difference in prevalence , extent , severity and prognosis of coronary artery disease among patients with and without diabetes undergoing coronary angiography.Diabetes Care 2012;35:1787-94. DOI: https://doi.org/10.2337/dc11-2403

Published

2019-06-21

How to Cite

1.
Mahwi T, Mirza A, Abdalwahid R. COMPARING CORONARY ANGIOGRAPHIC FINDINGS AMONG DIABETIC AND NON-DIABETIC PATIENTS. JSMC [Internet]. 2019 Jun. 21 [cited 2024 Jun. 19];9(2):141-8. Available from: https://jsmc.univsul.edu.iq/index.php/jsmc/article/view/jsmc-10200

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