PREVALENCE AND EFFECT OF IRON DEFICIENCY ANEMIA IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Keywords:Iron deficiency anemia, COPD, Exacerbation COPD, Chronic obstructive pulmonary disease
Anemia is progressively recognized as significant comorbidity in the context of chronic obstructive pulmonary disease (COPD).
To determine the extent of iron deficiency anemia in both exacerbation of COPD and stable COPD.
Patients and Methods
A prospective, multicenter, cross-sectional study was conducted between April 2017 and January 2018. Two groups of patients were enrolled, group A included those patients admitted in the emergency rooms for the management of acute exacerbation of COPD and group B comprised of those patients with stable COPD visited the consultatory medical department. Inclusion criteria included those patients known cases of COPD and categorized according to the GOLD criteria.
The study included 150 patients. Group A contained 100 patients. Seventy-nine (79%) were male with a mean age and standard deviation of 66.77 years ± 12.07 years. While the other groups (group B) comprised of 50 patients, 39 (78%) were male with a mean age of 59.86 years ± 9.87 years. The inflammatory marker was significantly more positive in group A (89, 89%) compared to group B (6, 12%), P-value 0.0001. Overall, the low iron profile was found in 15 (15%) patients in group A, and in 2 (4%) patients in group B (P-value 0.0559). Both iron and non-iron deficiency anemia were more prevalent among the exacerbation group (group A).
Anemia is a relatively common finding among COPD patients (both IDA and non-IDA). It is more prevalent among those patients developing frequent exacerbations.
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