A CASE OF BICKERSTAFF’S BRAINSTEM ENCEPHALITIS IN CHILDHOOD

Authors

  • Khalid Hama Salih Department of Pediatrics, School of Medicine, Faculty of Medical Sciences, University of Sulaimani, Kurdistan Region, Iraq.

DOI:

https://doi.org/10.17656/jsmc.10080

Keywords:

Encephalitis, Bickerstaff’s, Brain stem, Complete recovery

Abstract

Bickerstaff’s brainstem encephalitis is characterized by acute progressive ophthalmoplegia, ataxia, and disturbance of consciousness. It is similar to Miller Fisher syndrome, a variant of Guillain-Barre syndrome, because they have some features in common like; ophthalmoplegia and ataxia. The difference is that patients with Bickerstaff’s brainstem encephalitis have impaired consciousness and hyperreflexia while patients with Miller Fisher syndrome have alert consciousness and areflexia.

Here, we present a case 4 year and 3 month old girl with abrupt onset ophthalmoplegia, ataxia and disturbed consciousness, her brain Magnetic Resonance Imaging (MRI) was normal, cerebrospinal fluid analysis showed albuminocytological dissociation, and Nerve conduction study is suggestive of Acute Inflammatory Demyelinating-axonal motor polyneuropathy (AIDP). She has been treated successfully with steroid with complete recovery within two months.

References

Al-Din AN, Anderson M, Bickerstaff ER, Harvey I. Brainstem encephalitis and the syndrome of Miller Fisher: a clinical study. Brain : a journal of neurology. 1982;105 (Pt 3):481-95. DOI: https://doi.org/10.1093/brain/105.3.481

Odaka M, Yuki N, Yamada M, Koga M, Takemi T, Hirata K, et al. Bickerstaff’s brainstem encephalitis: clinical features of 62 cases and a subgroup associated with Guillain-Barre syndrome. Brain : a journal of neurology. 2003;126 (Pt 10):2279-90. DOI: https://doi.org/10.1093/brain/awg233

Bickerstaff ER, Cloake PC. Mesencephalitis and rhombencephalitis. British medical journal. 1951;2(4723):77-81. DOI: https://doi.org/10.1136/bmj.2.4723.77

Fisher M. An unusual variant of acute idiopathic polyneuritis (syndrome of ophthalmoplegia, ataxia and areflexia). The New England journal of medicine. 1956;255(2):57-65. DOI: https://doi.org/10.1056/NEJM195607122550201

Falini A, Kesavadas C, Pontesilli S, Rovaris M, Scotti G. Differential diagnosis of posterior fossa multiple sclerosis lesions--neuroradiological aspects. Neurological sciences. 2001;22 Suppl 2:S79-83. DOI: https://doi.org/10.1007/s100720100040

Belshe RB. Implications of the emergence of a novel H1 influenza virus. The New England journal of medicine. 2009;360(25):2667-8. DOI: https://doi.org/10.1056/NEJMe0903995

Williams MH. The spectrum of IgG GQ1(b) syndrome: an unusual cluster. Journal of clinical neuroscience. 2001;8(4):315-8. DOI: https://doi.org/10.1054/jocn.2000.0831

Ozawa T, Onodera O, Inuzuka T, Soma Y, Tsuji S. Efficacy of early plasmapheresis in Bickerstaff’s encephalitis. Intern Med. 1998;37(11):986-9. DOI: https://doi.org/10.2169/internalmedicine.37.986

Odaka M, Yuki N, Hirata K. Anti-GQ1b IgG antibody syndrome: clinical and immunological range. Journal of neurology, neurosurgery, and psychiatry. 2001;70(1):50-5. DOI: https://doi.org/10.1136/jnnp.70.1.50

Yaqub BA, al-Deeb SM, Daif AK, Sharif HS, Shamena AR, al-Jaberi M, et al. Bickerstaff brainstem encephalitis. A grave non-demyelinating disease with benign prognosis. Journal of the neurological sciences. 1990;96(1):29-40. DOI: https://doi.org/10.1016/0022-510X(90)90054-Q

Mondejar RR, Santos JM, Villalba EF. MRI findings in a remitting-relapsing case of Bickerstaff encephalitis. Neuroradiology. 2002;44(5):411-4. DOI: https://doi.org/10.1007/s00234-001-0733-3

Published

2015-12-01

Issue

Section

Articles

How to Cite

1.
Salih K. A CASE OF BICKERSTAFF’S BRAINSTEM ENCEPHALITIS IN CHILDHOOD. JSMC [Internet]. 2015 Dec. 1 [cited 2024 Jul. 19];5(2):155-9. Available from: https://jsmc.univsul.edu.iq/index.php/jsmc/article/view/jsmc-10080

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