• Aspazija Sofijanova University Children’s Hospital, Skopje, North Macedonia.
  • Olivera Jordanova University Children’s Hospital, Skopje, North Macedonia.
  • Khalaf H. Hasan Hivi Pediatric Teaching Hospital-Iraq, College of Medicine, University of Duhok, Kurdistan Region, Iraq.



Severe encephalitis, Infant, COVID-19


Encephalitis is a severe condition that consists of neurological dysfunction caused by inflammation of the brain tissue. Etiological factors for the occurrence of this condition include infectious and non-infectious causes.


A nine-month-old infant was referred to the hospital in a convulsive state, fever, and disturbed consciousness to the hospital objectives. From anamnestic information, the infant has been febrile for two days with protracted vomiting started just before admission at the hospital. At admission, the infant looked toxic with fever, shortness of breath, weak reaction to painful stimuli, and generalized tonic-clonic convulsions. He was admitted to the Isolation Unit by the protocol of the hospital. Laboratory investigations were done. Due to the persistence of the seizure, a CT scan of the brain was performed. It was showing dilated lateral ventricles, with intraventricular masses and pronounced internal hydrocephalus. The results of SARS-COV-2 from the infant were positive as well as the grandmother. The infant was intubated immediately and put on mechanical ventilation SIPPV.


SARS-CoV-2 infection may cause severe clinical symptoms, neurological manifestations, and encephalitis in infants.


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How to Cite

Sofijanova A, Jordanova O, Hivi K. SEVERE ENCEPHALITIS IN AN INFANT WITH COVID-19: A CASE REPORT. JSMC [Internet]. 2021 Sep. 21 [cited 2024 May 28];11(3):401-5. Available from:

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