FETAL ECHOCARDIOGRAPHY FOR RISKY PREGNANCIES IN SULAIMANI GOVERNORATE

Authors

  • Aso Faeq Salih Department of Pediatircs, College of Medicine, University of Sulaimani, Kurdistan Region, Iraq.

DOI:

https://doi.org/10.17656/jsmc.10113

Keywords:

Fetal echo, Congenotal heart disease, Gestational age

Abstract

Background

Prenatal diagnosis of congenital heart disease is now well established for a wide range of cardiacanomalies. Diagnosis of congenital heart disease during fetal life not only identifies the cardiac lesion but may alsolead to detection of associated abnormalities. This information allows a detailed discussion of the prognosis with parents. For continuing pregnancies, appropriate preparation can be made to optimize the post natal outcome.Morbidity and mortality, following antenatal diagnosis, has been reported for coarctation of the aorta, hypoplastic left heart syndrome, and transposition of the great arteries.

Objective

The aim of this prospective study is to evaluate our experience and results of fetal echo for high risk pregnancies in sulaimani city.

Methods

This is prospective descriptive study conducted on 450 pregnant ladies refered for fetal echocardiography from obstetricians , ultrasonographers and (self referral) from the 1st January 2013 to 1st the February 2017. Echocardiography done with Siemens machine with semicurved phased array probe at their first visit at 16-22 weeks in 330 ladies, at 22-28 weeks in 70 cases and at 31 weeks and above in 50 ladies. Also 2nd visit echo done for 60 patients for follow up at 31-33 weeks gestation. All babies checked post labour for accuracy of the diagnoses.

Results

Among 450 pregnant ladies, 98 cases found to have abnormal findings , of which 27 diagnosed as hypertrophic cardiomyopathy ( just one persist after 6 months post labour), 25 cases as ASD (just 10 left true ASD postlabour), 14 diagnosed as tricuspid atersia and single ventricle physiology, 5 AVSD , 5 arrhythmia with hydropis , 5 with MV and TV abnormalities, 4 AS, 3 hypoplastic left heart syndrome, 3 PS, 2 l-TGA and one Coa . For cases whom classify as low risk populations of defects no action undertaken, for high risk population decision for termination wan one of the options. 2 miss diagnosis observed after labour checking among anomalies observed echo findings and they were of low risk cases, and no miss diagnosis observed in major risk group diagnosed cases. Fetal echocardiography examination specifity was sensitivity as 97.9% and specifity as 99.4% which is within 95% CI, positive predictive value was 97.9%, negative predictive value was 99.4% in which both within 95% CI.

Conclusion

The present study showed that fetal echo has great value in detection of congenital heart disease, prognosis and outcome in high risk pregnancies. It’s recommended to familiarize our obstetrician about this important diagnostic test. We should train our ultrasonographer and pediatric cardiologist to increase awareness about this diagnostic test (is it screening test,or a diagnostic test). Also as far as we know this the first paper written on this kind of diagnostic technique , so more studies need to be conducted in the future.

References

Allan LD, Sharland GK, Milburn A, Lockhart SM, Groves AM,Anderson RH, et al. Prospective diagnosis of 1,006consecutive cases of congenital heart disease in the fetus.J Am Coll Cardiol 1994;23:1452-8. DOI: https://doi.org/10.1016/0735-1097(94)90391-3

Allan L, Dangel J, Fesslova V, Marek J, Mellander M,Oberhänsli I, et al. Recommendations for the practice offetal cardiology in Europe. Cardiol Young 2004;14:109-14. DOI: https://doi.org/10.1017/S1047951104001234

Bull C. Current and potential impact of fetal diagnosis onprevalence and spectrum of serious congenital heart diseaseat term in the UK. British Paediatric Cardiac Association.Lancet 1999;354:1242-7. DOI: https://doi.org/10.1016/S0140-6736(99)01167-8

Sharland G. Fetal cardiology. Semin Neonatol 2001;6:3-15. DOI: https://doi.org/10.1053/siny.2000.0030

Sharland G. What should be provided by a service for fetalcardiology? Cardiol Young 2000;10:625-35. DOI: https://doi.org/10.1017/S1047951100008921

Hyett J, Perdu M, Sharland G, Snijders R, Nicolaides KH.Using fetal nuchal translucency to screen for majorcongenital cardiac defects at 10-14 weeks of gestation:Population based cohort study. BMJ 1999;318:81-5. DOI: https://doi.org/10.1136/bmj.318.7176.81

Mavrides E, Cobian-Sanchez F, Tekay A, Moscoso G,Campbell S, Thilaganathan B, et al. Limitations of usingirst-trimester nuchal translucency measurement in routinescreening for major congenital heart defects. Ultrasound Obstet Gynecol 2001;17:106-10. DOI: https://doi.org/10.1046/j.1469-0705.2001.00342.x

Michailidis GD, Spencer K, Economides DL. The use ofnuchal translucency measurement and second trimesterbiochemical markers in screening for Down’s syndrome.BJOG 2001;108:1047-52. DOI: https://doi.org/10.1111/j.1471-0528.2001.00241.x

Huggon IC, Ghi T, Cook AC, Zosmer N, Allan LD, Nicolaides KH.Fetal cardiac abnormalities identiied prior to 14 weeks’gestation. Ultrasound Obstet Gynecol 2002;20:22-9.

Kumar RK, Newburger JW, Gauvreau K, Kamenir SA, Hornberger LK. Comparison of outcome when hypoplastic left heart syndrome and transposition of the great arteriesare diagnosed prenatally versus when diagnosis of these two conditions is made only postnatally. Am J Cardiol 1999;83:1649-53. DOI: https://doi.org/10.1016/S0002-9149(99)00172-1

Mahle WT, Clancy RR, McGaurn SP, Goin JE, Clark BJ. Impact of prenatal diagnosis on survival and early neurologic morbidity in neonates with the hypoplastic left heart syndrome. Pediatrics 2001;107:1277-82. DOI: https://doi.org/10.1542/peds.107.6.1277

Persico N, Moratalla J, Lombardi CM, Zidere V, Allan L, et al. (2011) Fetal echocardi-ography at 11-13 weeks by transabdominal highfrequency ultrasound. Ultrasound Obstetr Gynecol 37: 296-301. DOI: https://doi.org/10.1002/uog.8934

Jack R., Nancy A., Bettina C., Nina G., Lisa H., Philip J. S. et al . American Society of Echocardiography Guidelines and Standards for Performance of the Fetal EchocardiogramJ Am Soc Echocardiogr 2004;17:803-10. DOI: https://doi.org/10.1016/j.echo.2004.04.011

Tegnander E, Eik-Nes SH. The examiner’s ultrasoundexperience has a signiicant impact on the detection rateof congenital heart defects at the second-trimester fetalexamination. Ultrasound Obstet Gynecol 2006;28:8-14. DOI: https://doi.org/10.1002/uog.2804

Rustico MA, Benettoni A, D’Ottavio G, Fischer-Tamaro L,Conoscenti GC, Meir Y, et al. Early screening for fetalcardiac anomalies by transvaginal echocardiography in anunselected population: The role of operator experience.Ultrasound Obstet Gynecol 2000;16:614-9. DOI: https://doi.org/10.1046/j.1469-0705.2000.00291.x

Bryann B., Judy A.E., Stephen P.S., Richard P.,vDrucilla R., Fredric D.,Frigoletto Jr., Beryl R. B.. Fetal echocardiography: Accuracy and limitations in a population at high and low risk for heart defects,:American Journal of Obstetrics and Gynecology, Volume 166, Issue 5, May 1992, Pages 1473-1481 DOI: https://doi.org/10.1016/0002-9378(92)91622-H

Ingrid Stümpflen, Andreas Stümpflen, Maria Wimmer, Gerhard Bernaschek. Effect of detailed fetal echocardiography as part of routine prenatal ultrasonographic screening on detection of congenital heart disease ,The Lancet ,Volume 348, Issue 9031, 28 September 1996, Pages 854–857 DOI: https://doi.org/10.1016/S0140-6736(96)04069-X

C. HUGGON, T. GHI, A. C. COOK, N. ZOSMER, L. D. ALLAN and K. H. NICOLAIDES. Fetal cardiac abnormalities identified prior to 14 weeks’ gestation. Ultrasound Obstet Gynecol 2002; 20: 22–29 DOI: https://doi.org/10.1046/j.1469-0705.2002.00733.x

Burn J, Brennan P, Little J, Holloway S, Coffey R, Somerville J, Dennis NR, Allan L, Arnold R, Deanfield JE, Godman M, Houston A, Keeton B, Oakley C, Scott O, Silove E, Wilkinson J, Pembrey M, Hunter AS. Recurrence risks in offspring of adults with major heart defects: results from first cohort of British collaborative study. Lancet 1998; 351: 311–6 DOI: https://doi.org/10.1016/S0140-6736(97)06486-6

DeVore GR. Trisomy 21: 91% detection rate using second– trimester ultrasound markers. Ultrasound Obstet Gynecol 2000; 16: 133–41 DOI: https://doi.org/10.1046/j.1469-0705.2000.00203.x

DeVore GR. The genetic sonogram: its use in the detection of chromosomal abnormalities in fetuses of women of advanced maternal age. Prenat Diagn 2001; 21: 40–5 DOI: https://doi.org/10.1002/1097-0223(200101)21:1<40::AID-PD980>3.0.CO;2-U

Ventriglia F., Caiaro A., Giancotti A., Abed M., Ceccacci I., Celani S. et al . Reliability of Early Fetal Echocardiography for Congenital Heart Disease Detection: A Preliminary Experience and Outcome Analysis of 102 Fetuses to Demonstrate the Value of a Clinical Flow-Chart Designed for At-Risk Pregnancy Management. Pediat Therapeut 2016, 6:1 http://dx.doi.org/10.4172/2161-0665.1000270. DOI: https://doi.org/10.4172/2161-0665.1000270

Published

2017-08-15

How to Cite

1.
Salih A. FETAL ECHOCARDIOGRAPHY FOR RISKY PREGNANCIES IN SULAIMANI GOVERNORATE. JSMC [Internet]. 2017 Aug. 15 [cited 2024 Jul. 4];7(2):123-30. Available from: https://jsmc.univsul.edu.iq/index.php/jsmc/article/view/jsmc-10113

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