EVALUATION OF SERUM SODIUM LEVEL IN SINGLE AND RECURRENT FEBRILE SEIZURES

Authors

  • Ibrahim Khasraw Ghafoor Department of Pediatrics, College of Medicine, University of Sulaimani, Kurdistan Region, Iraq.

DOI:

https://doi.org/10.17656/jsmc.10140

Keywords:

Febrile seizures, Single and recurrent, Serum Sodium level

Abstract

Background 

Febrile seizures are the most common form of childhood seizures. Its either simple (when it is single attack within next 24 hours, plus other characters) or complex (when is recurrent within same period plus other characteristics).

Objectives

 

This study was conducted to determine the role of low serum sodium levels in predicting single or recurrent febrile seizures among children.

Patients and Methods

In this study, 100 patients aged 6-60 months old were enrolled. The patients were divided into two groups: those with single, and those with recurrent febrile seizures. Then 100 children with febrile illness, but no febrile convulsion, taken as a control. For those 3 groups serum sodium levels were studied.

Results

Among the patients, male gender was predominant. Among those with 12-24 months old, positive family history of febrile seizures was significant. The mean serum sodium of patients with single febrile seizure was (137.91), while the mean serum sodium level of patients with recurrent febrile seizures was (139), and the mean serum sodium of control group was (141.42). The P-value of comparison between control and those with single febrile seizure was significant (0.002), but the P-value of comparison between control and those with recurrent febrile seizures was not significant (0.813). There was no significant role of the serum sodium found during admission of the patients. 

Conclusion

We found in present study: there was no significant role for the serum sodium during single or recurrent F.S.s. These findings reaffirm the recommendation of the American Academy of Pediatrics not to routinely obtain serum electrolytes in febrile seizures unless clinically indicated.

References

-ShinnaS. Febrile seizures In: Swaiman kF, Ashwal S, Ferriero DM, editers. Pediatrics neurology : principle and practice.4thed.Philadelpha : Mosby Elsevier, 2006 P. 1078- 86.

-Guidelines for epidemiologic studies on epilepsy. Commission on Epidemiology and prognosis , International League Against Epilepsy (editorial).Epilepsy 1993:347 (4): 592-6 DOI: https://doi.org/10.1111/j.1528-1157.1993.tb00433.x

-Waruriu C, Applfton R. Febrile seizures: up date .Arch Dis CHILD 2004 : 89 (8): 751-6 DOI: https://doi.org/10.1136/adc.2003.028449

-Berg AT. Are febrile seizures provoked by a rapid rise in temperature ? Am j Dis child 1993: 147(10): 1101-3 DOI: https://doi.org/10.1001/archpedi.1993.02160340087020

-Behrman RE, Kliegman RM .Paroxysmal disorders. In :Kliegman RM ,Behrman RE, editors. Nelson Essential of pediatrics .5th . phliadelpha: Saunders, 2006. P.p838

-Mohammad A. Mikati and AbeerJ. Han: Febrile seizure in :Kliegman, Fanton,St Gene, Schor. Nelson textbookof pediatrics.20th edition, volume-2 philadelphia,Elsevier,2016:page 2829-30.

- Duffines PK, Baumann RJ.A synopsis of the American Academy of pediatrics , practice parameters on the evaluation and treatment of children with febrile seizures pediatr Rev 1999: 285-7 DOI: https://doi.org/10.1542/pir.20-8-285

- KivirantoT,Airaksinen EM. Low sodium levels in serum are associated with subsequent febrile seizures .Acta pediatr 1995: 84(12): 1372-4 DOI: https://doi.org/10.1111/j.1651-2227.1995.tb13571.x

-Hugen CA,Oudeslys-MarphyAM, HopWC. Serum sodium level and probability of recurrent febrile convulsion. Eur .J pediatr 1995: 154(5):403-5 DOI: https://doi.org/10.1007/BF02072115

-MUKHALD ABDUL-KAREEM GHANI .Evaluation of serum sodium levels in simple and recurrent febrile convulsions. A thesis submitted to the scientific council of pediatrics in partial fulfillment for the degree of fellowship of the Iraqi board for medical specialization in pediatrics.2014:34.

-Pal DK,Kugler SL,Mandelbaum DE,Durner M. Phenotypic features of familial febrile seizures:case-control study.Neurology2003;60(3):410-4. DOI: https://doi.org/10.1212/WNL.60.3.410

-Al-Atrushi A, Abdurahman K. The association between iron deficiency anemia and first febrile seizure .Duhok Med j2010

- Hauser WA. The prevalence and incidence of convulsion disorders in children .Epilepsy 1994;35 (2):S1-6x DOI: https://doi.org/10.1111/j.1528-1157.1994.tb05932.x

-Abvekteish F, Daoud As, Al-SheyyabM, NoumanM. Demographic characteristic and risk factors of febrile seizures : a Jordanian experience. Trop Doc 200:30:25-27 DOI: https://doi.org/10.1177/004947550003000113

-Berg AT, ShinnarS, Complex febrile seizure. Epilepsia 1996:37(2):126-33. DOI: https://doi.org/10.1111/j.1528-1157.1996.tb00003.x

-Laditan AA. Seizure recurrent after a first febrile convulsion. Ann Trop paediatr.1994;14(4)303-308. DOI: https://doi.org/10.1080/02724936.1994.11747733

-Martin-Fernandez JJ, Moito-Jorda JM et al. Risk factors n recurrent febrile seizures. Rev Neurol. 1996;24(136):1520-1524

-Offringo M, Derksen- Lubsen G et al. Risk factors for the occurrence of recurrent convulsions following a febrile convulsion. Ned Tijdschr Geneesked.1992; 136(11):516-521.

-Al-Eissa YA. Febrile seizures: rate and risk factors or recurrence. J child Neural 1995;10(10):315-319 DOI: https://doi.org/10.1177/088307389501000415

-Knudsen FU.Recurrence risk after first febrile seizure and effect of short term diazepam prophylaxis Arch Dis child 1985;601045-49. DOI: https://doi.org/10.1136/adc.60.11.1045

-Mohammad A. Mikati and AbeerJ. Han: febrile seizure in :Kliegman, Fanton,St Gene, Schor. Nelson textbookof pediatrics.20th edition, volume-2 philadelphia,Elsevier,2016:page 2829-30.

-Bessissco MS, EI said MF,Almula NA et al.Recurrence risk after a first febrile convulsion. Saudi Medical journal 2001:22(3):254-258.

-Tsuboi T.Seizures of childhood. Acto Neurol Scand 1986;74:12-37. DOI: https://doi.org/10.1111/j.1600-0404.1986.tb04427.x

-Thoman JE,Duffiner PK,Shukurd JL.Do serum sodium levels predict febrile seizure recurrence within 24hours?Pediatr Neurol 2004;31(5):342-4. DOI: https://doi.org/10.1016/j.pediatrneurol.2004.05.013

-American Academy of Pediatrics,Provisional Committee on Quality Improvement and Sub committee on Febrile Seizures .Practice Parameter:the neuro diagnostic evaluation of a child with a first simple febrile seizure.Pediatrics 2011;127:389-94. DOI: https://doi.org/10.1542/peds.2010-3318

Published

2017-12-21

How to Cite

1.
Ghafoor I. EVALUATION OF SERUM SODIUM LEVEL IN SINGLE AND RECURRENT FEBRILE SEIZURES. JSMC [Internet]. 2017 Dec. 21 [cited 2024 Jul. 3];7(4):371-7. Available from: https://jsmc.univsul.edu.iq/index.php/jsmc/article/view/jsmc-10140

Similar Articles

1-10 of 167

You may also start an advanced similarity search for this article.