THE ASSOCIATION BETWEEN THE PREMENSTRUAL SYNDROME WITH VITAMIN D AND CALCIUM STATUS AMONG UNIVERSITY STUDENTS

Authors

  • Maryam Bakr Mahmood Department of Obstetrics and Gynaecology, College of Medicine, University of Sulaimani, Kurdistan Region, Iraq.
  • Mayda Y. Shamdeen Department of Obstetrics and Gynecology, School of Medicine, Dohuk University, Kurdistan Region, Iraq.
  • Tavge Rawf Abdulrahman Sulaimani Maternity Teaching Hospital, Sulaimani City, Kurdistan Region, Iraq.

DOI:

https://doi.org/10.17656/jsmc.10211

Keywords:

Premenstrual Syndrome, Vitamin D, Serum Calcium

Abstract

Background 

Premenstrual syndrome causes both psychological and physiological adverse effects on women in reproductive age. Calcium and vitamin D may have an effect on the development of premenstrual syndrome through their relationship to endogenous estrogen.

Objectives 

The current study aimed to assess student’s calcium serum level and vitamin D level and determine their relation with premenstrual syndrome among Sulaimani University students.

Material and Method

This observational study included 42 female students (21 participants diagnosed with Premenstrual syndrome and 21 participants as their controls) within the age ranges from 21-29 years who were students in Sulaimani University from March 2018 to March 2019. Serum level of Calcium and vitamin D were measured for each of them. Data collected by questionnaire form and data analysed by SPSS and for the relationship between variables Chi-square and T-test used.

Results

Students in both of control and premenstrual syndrome cases had a deficient level of vitamin D, with the level of 15.51±8.64 ng/ml and 13.09±6.02 ng/ml subsequently with non-significant relation. The level of serum calcium was below normal range in the premenstrual syndrome group (8.21±3.3 mg/dl) compare with the control group (9.01±0.47 mg/dl) was in normal range with significant relationship between case and control group (P-value 0.03).

Conclusion

The mean level of vitamin D was below the normal range in both case and control groups but they were lower in Premenstrual Syndrome cases compared with control cases among students in Sulaimani University and the mean level of serum calcium was low in case group with significant relation between case and control groups.

References

Rapkin AJ, Akopians AL. Pathophysiology of premenstrual syndrome and premenstrual dysphoric disorder. Menopause Int. 2012 Jun;18(2):52-9. DOI: https://doi.org/10.1258/mi.2012.012014

Bakhshani NM, Mousavi MN, Khodabandeh G. Prevalence and severity of premenstrual symptoms among Iranian female university students. J Pak Med Assoc. 2009 Apr;59(4):205-8.

Dickerson LM, Mazyck PJ, Hunter MH. Premenstrual syndrome. Am Fam Physician. 2003;67(8):1743-52.

Edmonds DK, Lees C, Bourne TH, editors. Dewhurst's textbook of obstetrics & gynaecology. Blackwell Pub.; 2007 Sep 20. DOI: https://doi.org/10.1002/9780470753354

Green LJ, O’Brien P, Panay N, Craig M. Management of Premenstrual Syndrome. BJOG. 2017;124(3):e73-e105. DOI: https://doi.org/10.1111/1471-0528.14260

Thys-Jacobs S. Micronutrients and the premenstrual syndrome: the case for calcium. J Am Coll Nutr.. 2000 Apr 1; 19(2):220-7. DOI: https://doi.org/10.1080/07315724.2000.10718920

Thys-Jacobs S, Starkey P, Bernstein D, Tian J, Premenstrual Syndrome Study Group. Calcium carbonate and the premenstrual syndrome: effects on premenstrual and menstrual symptoms. Am J Obstet Gynecol. 1998 Aug 1; 179(2):444-52. DOI: https://doi.org/10.1016/S0002-9378(98)70377-1

Kia AS, Amani R, Cheraghian B. The association between the risk of premenstrual syndrome and vitamin D, calcium, and magnesium status among university students: a case control study. Health promotion perspectives. 2015;5(3):225. DOI: https://doi.org/10.15171/hpp.2015.027

Chakhtoura M, Rahme M, Chamoun N, El-Hajj Fuleihan G. Vitamin D in the Middle East and North Africa. Bone Rep. 2018; 8:135-46. DOI: https://doi.org/10.1016/j.bonr.2018.03.004

Bertone-Johnson ER, Hankinson SE, Bendich A, Johnson SR, Willett WC, Manson JE. Calcium and vitamin D intake and risk of incident premenstrual syndrome. Arch Intern Med. 2005;165(11):1246-52. DOI: https://doi.org/10.1001/archinte.165.11.1246

Akhlaghi F, Hamedi A, Javadi Z, Hosseinipoor F. Effects of calcium supplementation on premenstrual syndrome. Razi Journal of Medical Sciences. 2004; 10(37):669-75.

Mandana Z, Azar A. Comparison of the Effect of Vit E, VitB6, Calcium and Omega-3 on the Treatment of Premenstrual Syndrome: A Clinical Randomized Trial. Annual Research & Review in Biology. 2014;4(7):1141-9. DOI: https://doi.org/10.9734/ARRB/2014/7503

Published

2019-09-21

How to Cite

1.
Mahmood M, Shamdeen M, Abdulrahman T. THE ASSOCIATION BETWEEN THE PREMENSTRUAL SYNDROME WITH VITAMIN D AND CALCIUM STATUS AMONG UNIVERSITY STUDENTS. JSMC [Internet]. 2019 Sep. 21 [cited 2024 Jun. 13];9(3):239-43. Available from: https://jsmc.univsul.edu.iq/index.php/jsmc/article/view/jsmc-10211

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