THE RELATIONSHIP BETWEEN CENTRAL CORNEAL THICKNESS AND DEGREE OF AXIAL MYOPIA AMONG PATIENTS ATTENDING SHAHEED DR. ASO TEACHING HOSPITAL
DOI:
https://doi.org/10.17656/jsmc.10104Keywords:
Central corneal thickness, axial myopia, optical low-coherence reflectometry, PachymeterAbstract
Background
Central corneal thickness (CCT) is an important indicator of corneal health status. Myopia is the refractive state in which parallel rays of light from a distant object are brought to focus in front of the retina in the non-accommodating eye. Since, both cornea and sclera are continuous layers the thinner cornea would also be expected.
Objectives
The aim of this study is to determine whether there is an association between central corneal thickness and degree of axial myopia.
Subjects and Methods
This cross sectional study encompasses 103 patients (203 eyes) of emmetropic control group and 100 patients (197 eyes) of myopic group. The subjects had slit lamp examination for both eyes, including lids, conjunctiva, cornea, anterior chamber, pupil, iris, lens and fundus; best spectacle corrected visual acuity (BSCVA) refraction, and intraocular pressure (TOPCON computerized tonometer). Axial lengths, central corneal thickness, and keratometry reading were measured by a LENSTAR LS900 machine (HAAG-STREIT).
Results
The Mean CCT + SD for the emmetropic group was (539.35 ±28.98 μm), and for the axial myopic group (533.22 ±32.27μm). The mean CCT from the two groups showed a statistically significant difference (p = 0.047). However there is no significant correlation between mean CCT and the degree of axial myopia (r = 0.013, P = 0.109).
Conclusion
Central corneal thickness has no statistically significant correlation with degree of axial myopia.
References
Congdon NG, Broman AT, Bandeen-Roche K, Grover D, Quigley HA. Central corneal thickness and corneal hysteresis associated with glaucoma damage. Am J Ophthalmol. 2006 May; 141(5):868-75. Epub 2006 Mar 9. https://www.ncbi.nlm.nih.gov/pubmed/16527231. Accessed December 3, 2016 DOI: https://doi.org/10.1016/j.ajo.2005.12.007
Brad Bowling, chapter 10 glaucoma. In: Brad Bowling, editor. Kanski’s Clinical Ophthalmology. 8th ed. Sydney: Elsevier; 2016. p.309.
Pallikaris IG, Kymionis GD, Astyrakakis NI. Corneal ectasia induced by laser in situ keratomileusis. J Cataract Refract Surg, 2001; 27:1796–1802. DOI: https://doi.org/10.1016/S0886-3350(01)01090-2
Thomas J. Liesegang, Gregory L. Skuta, Louis B, et al, Refractive States of the Eyes. San Francisco: American Academy of Ophthalmology, 2014; 83.
Yanoff. M, Duker, J. S. Ophthalmology. 3rd ed. Mosby; 2004: p.61.
Thomas J. Liesegang, Gregory L. Skuta, Louis B. Cantor. Refractive Management/Intervention Panel. Preferred Practice Pattern Guidelines. Refractive Errors. San Francisco: American Academy of Ophthalmology, 2002.
McCarty C, Taylor HR. Myopia and vision 2020. Am J Ophthalmol, 2000; 129(4):525- 27. DOI: https://doi.org/10.1016/S0002-9394(99)00444-4
Winawer J, Wallman J, Kee C. Differential responses of ocular length and choroidal thickness in chick eyes to brief periods of plus and minus lens-wear. Invest Ophthalmol, 1999; 40:p.963.
Lene Pedersen, Jesper Hjortdal, Niels Ehlers. Central corneal thickness in high myopia. Arhus: Acta Ophthalmologica Scandinavica, 2005; 83(5):p.539-42. DOI: https://doi.org/10.1111/j.1600-0420.2005.00498.x
Phillips JR, McBrien NA. Form deprivation myopia: elastic properties of sclera. Ophthalmic Physiol Opt, 1956; 15:357–62. DOI: https://doi.org/10.1046/j.1475-1313.1995.9500062i.x
Al-Mezaine HS, Al-Obeidan S, Kangave D, Sadaawy A, Wehaib TA, Al-Amro SA. The relationship between central corneal thickness and degree of myopia among Saudi adults. International ophthalmology, 2009; 29(5): p 373-78.at: https://www.ncbi.nlm.nih.gov/pubmed/18587538, Accessed December 6, 2016 DOI: https://doi.org/10.1007/s10792-008-9249-8
T Lifshitz, J Levy, S Rosen, N Belfair , S Levinger, Central corneal thickness and its relationship to the patient's origin." Eye; 2006; 20(4): p. 460-65., http://www.nature.com/eye/journal/v20/n4/full/6701911a.html. Accessed December 6, 2016 DOI: https://doi.org/10.1038/sj.eye.6701911
Liu Z, Pflugfelder SC. The effects of long-term contact lens wear on corneal thickness, curvature, and surface regularity. Ophthalmology, 2000; 107:105–11. DOI: https://doi.org/10.1016/S0161-6420(99)00027-5
Tokoro T, Hayashi K, Muto M, Central corneal thickness in high myopia. Folia Ophthalmol Jap, 1976; 27:610.
Von Bahr G. Corneal thickness: its measurement and changes. Am J Ophthalmol, 1956; 42: p.251–66 DOI: https://doi.org/10.1016/0002-9394(56)90928-X
Ehlers N, Bramsen T, Sperling S. Applanation tonometry and central corneal thickness. Acta Ophthalmol (Copenhagen), 1975; 53:34–43. DOI: https://doi.org/10.1111/j.1755-3768.1975.tb01135.x
Shimmyo M, Ross AJ, Moy A, Mostafavi R. Intraocular pressure, Goldmann applanation tension, corneal thickness and corneal curvature in Caucasians, Asians, Hispanics and African Americans. Am J Ophthalmol, 2003; 136: p.603, p.613-16. DOI: https://doi.org/10.1016/S0002-9394(03)00424-0
Price FW Jr, Koller DL, Price MO. Central corneal pachymetry in patients undergoing laser in situ keratomileusis. Ophthalmology, 1999; 106: p.2216–2220. DOI: https://doi.org/10.1016/S0161-6420(99)90508-0
Cho P, Lam C. Factors affecting the central corneal thick-ness of Hong Kong-Chinese. Curr Eye Res, 1999; 18:368-74. DOI: https://doi.org/10.1076/ceyr.18.5.368.5347
Alsbirk PH. Corneal thickness. I: Age variation; sex difference and oculometric correlations. Acta Ophthalmol (Copenhagen), 1978; 56:95–104. DOI: https://doi.org/10.1111/j.1755-3768.1978.tb00471.x
Kunert KS, Bhartiya P, Tandon R, et al. Central corneal thickness in Indian patients undergoing LASIK for myopia. J Refract Surg, 2003; 19:p.378-9. DOI: https://doi.org/10.3928/1081-597X-20030501-18
Chang SW, Tsai IL, Hu FR, et al. The cornea in young myopic adults. Br JOphthalmol 2001; 85:p.916-20. DOI: https://doi.org/10.1136/bjo.85.8.916
Srivannaboon S. Relationship between corneal thickness and level of myopia. J Med Assoc Thai, 2002; 85:162-66.
Touzeau O, Allouch C, Borderie V, et al. Correlation be-tween refraction and ocular biometry. J Fr Ophtalmol, 2003; 26:p.355-63.
Martola EL, Baum JL. Central and peripheral corneal thickness: a clinical study. Arch Ophthalmol 1968; 79:p.28-30. DOI: https://doi.org/10.1001/archopht.1968.03850040030009
Hansen FK. A clinical study of the normal human central corneal thickness. Acta Ophthalmol (Copenhagen) 1971; 49:82-9. DOI: https://doi.org/10.1111/j.1755-3768.1971.tb00971.x
H-B FAM, A C S How, M Baskaran, K-L Lim, Y-H Chan, and T Aung. Central corneal thickness and its relationship to myopia in Chinese adults. Br J Ophthalmol 2006; 90:1451-1453. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1857527/.Accessed December 6, 2016 DOI: https://doi.org/10.1136/bjo.2006.101170
Aghaian E, Choe JE, Lin S, Stamper RL. Central corneal thickness of Caucasians, Chinese, Hispanics, Filipinos, African Americans and Japanese in a glaucoma clinic. Ophthalmology, 2004; 111:p.2211–2219.https://www.ncbi.nlm.nih.gov/pubmed/15582076. Accessed December 6, 2016 DOI: https://doi.org/10.1016/j.ophtha.2004.06.013
Khaja WA, Grover S, Kelmenson AT, Ferguson LR, Sambhav K, Chalam KV. Comparison of central corneal thickness: ultrasound pachymetry versus slit-lamp optical coherence tomography, specular microscopy, and Orbscan.Clinical Ophthalmology (Auckland, NZ). 2015; 9:p.1065-1070. https://www.ncbi.nlm.nih.gov/pubmed/26109840. Accessed December 6, 2016 DOI: https://doi.org/10.2147/OPTH.S81376
Downloads
Published
Issue
Section
License
Copyright (c) 2017 Ali Abdullah Taqi Al- Saffar, Yaseen Ahmed Ali
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
This work is licensed under 