MYELOID SARCOMA PRESENTING AS SKIN NODULES IN SULAYMANIYAH CITY

Volume 13 , Issue 4 , July 2025 , Pages 483-486

Authors

Kani Delawer 1 ; Hisham Arif Getta 2 ; Dana N. Muheadeen 3

1 Dept. of Hematopathology, Hiwa Cancer Hospital, Ministry of Health, Kurdistan Region, Iraq.

2 Dept. of Pathology. College of Medicine, University of Sulaimani, Kurdistan Region, Iraq.

3 Dept. of Pathology, Shorsh General Hospital, Hiwa Cancer Hospital, Ministry of Health, Kurdistan Rgion, Iraq.

DOI logo 10.17656/jsmc.10443

Keywords

Abstract

Myeloid sarcoma is a rare malignant myeloid tumour known as granulocytic sarcoma or chloroma. As not
all myeloid leukaemias are derived from granulocytes, the preferred term is myeloid sarcoma instead of
granulocytic sarcoma and chloroma, consisting of the myeloid blast with or without maturation. Myeloid
sarcoma may occur de novo or precede or be associated with acute or chronic myeloid leukaemias, or represent
a blast transformation of myeloproliferative disorders, myelodysplastic syndromes, or it may represent
a relapsed state in patients diagnosed previously as AML regardless of blood or BM fi ndings. It is more
common in adults between 45 and 55 years of age. Myeloid sarcoma can involve any body site other than
the bone marrow that totally or partially effaced the tissue architecture. The most affected sites are lymph
nodes, skin, and bones (1). Skin, soft tissues, bone, lymph nodes, GIT, and testis are common sites to be
involved (2). Occurrence in the other sites like skull bones, orbit, and paranasal sinuses is unusual (3). The
pathogenesis of this sarcoma is believed to be an aberrant expression of homing signals for the leukemic blasts
on extramedullary sites compared to bone marrow.

Statistics
  • Article view487
  • Downloads0
  • First online26 July 2025
  • Published at26 July 2025

  • RIS
  • BibTeX
  • EndNote
  • Mendeley
  • APA (7th edition)
  • MLA (9th edition)
  • Chicago
  • Harvard
  • IEEE
  • Vancouver