SEROPREVALENCE OF ANTI-RESPIRATORY SYNCYTIAL VIRUS ANTIBODIES IN HOSPITALIZED PATIENTS WITH ACUTE RESPIRATORY TRACT INFECTIONS IN SULAIMANI GOVERNORATE IRAQ
Volume 4 , Issue 1 , June 2014 , Pages 47-53
Authors
Tariq A. G. Aziz 1 ; Ali Hattem Hussain 2
1 Department of Microbiology, School of Medicine, Faculty of Medical Sciences, University of Sulaimani
2 Sulaimani Technical College, Sulaimani Polytechnic University.
10.17656/jsmc.10048
Keywords
Abstract
Background
Respiratory syncytial virus (RSV) is a major respiratory pathogen among children, and it is a leading cause of bronchiolitis and pneumonia among hospitalized children.
Objectives
To measure the seroprevalence of anti-RSV antibodies among hospitalized children presenting with acute respiratory tract infections in Sulaimani Governorate, Kurdistan/Iraq.
Methods
ELISA technique was used to detect serum anti-RSV antibodies (IgM and IgG antibodies) from 300 hospitalized children less than 5 years old with a diagnosis of acute respiratory tract infections.
Results
IgM anti-RSV was positive in 61 (20.3%) out of 300 children. The highest seroprevalence was found in the age group 1 to < 2 years, while the lowest in the age group 2 to < 3 years. No significant gender difference was found among seropositive children. The IgM anti – RSV seropositive children were suffering from bronchiolitis, pneumonia, or other respiratory tract infections in a frequency of 29 (47.5%), 15 (24.6%), and 17 (27.9%). The IgG anti-RSV antibodies were positive in 216 (72%) out of the 300 children, and there was a gradual increase in percentage of seropositivity with increasing age.
Conclusion
RSV is a common viral respiratory pathogen among hospitalized children in Sulaimani governorate/ Kurdistan/Iraq, and most of the children had experienced RSV infection by the age of five years.
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