CORRELATION BETWEEN ULTRASONOGRAPHICALLY NEGATIVE AXILLARY LYMPH NODES AND SENTINEL LYMPH NODE BIOPSY RESULTS IN BREAST CANCER PATIENTS

Volume 14 , Issue 1 , March 2024 , Pages 41-46

Authors

Sozan Hama Yousif Zorab Muhamad 1 ; Kawa Abdulla Mahmood 2

1 Department of Radiology and Medical Imaging, Sulaymaniyah Teaching Hospital, Ministry of Health, Sulaymaniyah City, Kurdistan Region, Iraq.

2 Department of Radiology and Medical Imaging, College of Medicine, University of Sulaimani, Kurdistan Region, Iraq.

DOI logo 10.17656/jsmc.10449

Keywords

Abstract

Background
The most crucial factors in overall prognosis and disease-free survival of breast cancer cases are the status of
axillary lymph nodes and tumour size. Substantial focus has recently been given to identifying less invasive
techniques for diagnostic reasons. Ultrasound imaging is the most widely used complement to axillary surgical
staging.
Objectives
A retrospective study was conducted on patients with breast cancer who had negative axillary lymph nodes on
ultrasound; we tried to correlate the results of the pathological nodal status of SLNB, which was done as part
of the staging process.
Methods
A cross-sectional retrospective study was conducted on registered breast cancer patients at Shar Teaching
Hospital in 2021-2022. The correlation between the negative axillary ultrasound (AUS) result and the
pathological result of SLNB was analyzed. Variables studied included the tumour size and stage, histological
subtype and pathological nodal stage. A total of 80 cases were reviewed; the aim was to detect the negative
predictive value (NPV) of PAUS and its false negative rate. IBM SPSS Statistics Version 22 was used for the
statistical analyses of the data.
Results
Eighty-two female breast cancer patients with negative AUS went through SLNB. The mean age of
the participants was 50. Half of the patients (n=41) were premenopausal, and half of them (n=41) were
postmenopausal. The SLNB results were negative in 73 patients (NPV of PAUS was 89.0%) and were positive
in 9 patients (False-negative rate of PAUS was 11.0%). Positive histopathological results were as follows: 2
cases (2.4%) had isolated tumour cells (pN0i+), 2 cases (2.4%) had micro-metastasis (pN1mic), and 5 cases
(6.1%) had macro-metastasis (pN1a).
Conclusion
PAUS, as a noninvasive modality for axillary lymph node staging, has a high NPV in breast cancer patients.

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  • Published at21 March 2024

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