THE WEIGHT-REDUCING EFFECT OF ENDOSCOPICALLY – INSERTED INTRAGASTRIC BALLOONS FOR OBESE PATIENTS FAILED WEIGHT CONTROL WITH LIFESTYLE MODIFICATION AND DRUGS

Volume 13 , Issue 1 , March 2023 , Pages 75-81

Authors

Hiwa Abubakr Hussein 1 ; Bakhtyar Faiq Salim 1 ; Mohammad Abdul Rahman AlShaikhani 1 ; Aziz Qadir Sleman 2

1 College of Medicine. University of Sulaimani, Kurdistan Region, Iraq.

2 Directorate of Health of Sulaimani, Ministry of Health. Kurdistan Region. Iraq.

DOI logo 10.17656/jsmc.10399

Keywords

Abstract

Background
The Food and Drug Administration (FDA) recently approved three intragastric balloons (IGB) devices,
ReShape, ORBERA™, and Obalon, for treating obesity. Given the high cost, complication risk, and invasiveness
of bariatric surgery, IGB treatment may present a safer and lower-cost option for weight reduction. IGBs
are generally placed in the stomach endoscopically for up to 6 months to reduce gastric capacity, enhance
feelings of fullness, and induce weight loss. The mechanism of action likely involves stimulation of gastric
mechanoreceptors triggering short-acting vagal signals to brain regions implicated in satiety. Balloon efficacy
may be influenced by balloon volume, patient gastric capacity, and treatment duration.
Objectives
To evaluate the efficacy, tolerability, and safety of intra-gastric balloons on weight reduction versus obese
patients’ failed weight controlled by dietary changes and drugs.
Methods
A retrospective study was performed in Sulaimani City from 2017 to Feb./2018. We included 40 obese patients
by the World Health Organization (WHO) definition of BMI≥30. The subjects aged 18-68 years with intragastric balloons were inserted by endoscopy for 4-9 months. Anthropometric measurements were obtained
before, during and after the removal of intra-gastric balloons.
Results
In total, 40 cases of obese patients, 21 (52.5%) females and 19 (47.5%) males. The mean age was 37.1±11.70years
with a range of 18-68 years. BMI and weight significantly reduced early 3-month mean weight 12.78±2.81 Kg,
and late 6-month mean weight 9.05±1.89 Kg and around 21 Kgs at removal. Only one patient was the IGB
removed early by four months and was not included. Late one year after IGB removal, the long-term effect on
BMI and weight were recorded and maintained in most persons.
Conclusion
Intragastric balloon (IGB) was effective in our study. The observed weight reduction was maintained through
1 year after removal & IGB appeared safe and tolerable & satisfactory for most obese subjects.

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  • Published at21 March 2023

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