REVISION OF MULTIPLE SCLEROSIS CASES ACCORDING TO NEW 2017 MCDONALD CRITERIA AMONG DIAGNOSED PATIENTS IN SULAIMANI CITY

Volume 11 , Issue 3 , September 2021 , Pages 323-333

Authors

Rzgar Hamid Abdula 1 ; Mohammed Tahir Kurmanji 2 ; Zana A.Mohammed 2 ; Sarwer Jamal Al-Bajalan 2

1 Department of Neurology of Shar Teaching Hospital, Kurdistan Region, Iraq.

2 Department of Medicine, College of Medicine, University of Sulaimani, Kurdistan Region, Iraq.

DOI logo 10.17656/jsmc.10317

Keywords

Abstract

Background
Multiple sclerosis (MS) is a chronic, immune-mediated inflammatory disorder of the central nervous system.
The diagnosis of Multiple sclerosis is challenging, owing to having a comprehensive list of differentials and
mimickers.
Objectives
To determine the frequency of misdiagnosed Multiple Sclerosis cases diagnosed among those patients in
Sulaimani city.
Patients and and Methods
This retrospective observational study was conducted within a period between December 24th. 2019 and
June 10th, 2020, on 106 already diagnosed patients. The study included patients diagnosed with the relapseremitting form of multiple sclerosis. We excluded those patients with progressive forms of multiple sclerosis.
We re-evaluated each patient in-depth and stratified the cases according to the diagnosis certainty based on the
fulfillment of the 2017 McDonald Criteria. Finally, we returned those suspicious cases to the multiple sclerosis
committee of Shar hospital to verify their final diagnosis.
Results
Sixteen (16.9%) out of 106 patients, there was diagnostic uncertainty in which 6 (5.7%) of them received the
confirmatory diagnosis of relapse-remitting multiple sclerosis by the committee, and 1(0.9%) patient considered
secondary progressive multiple sclerosis. In the remaining 9 (8.4%) patients, we found the clinically isolated
syndrome in 5 (4.7%) patients, solitary sclerosis in 1 (0.9%) patient, stroke with polycythemia rubra vera
(PRV) in 1 (0.9%) patient, possible cerebral autosomal dominant arteriopathy with subcortical infarcts and
leukoencephalopathy in 1 (0.9%) patient, and 1 (0.9 %) patient was undiagnosed.
Conclusion
To sum up, the frequency of multiple sclerosis misdiagnosis was 8.4% in Sulaimani city, slightly lower than
the other reporting centers

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