PATTERN AND PROGRESSION OF CHRONIC KIDNEY DISEASE IN A GROUP OF PATIENTS IN SULAIMANI CITY

Authors

  • Neiran Munthir Family of Medicine, Qatae Hospital, Ministry of Health, Musil, Kurdistan Region, Iraq.
  • Dana A. Sharif College of Medicine, University of Sulaimani, Kurdistan Region, Iraq.
  • Serwan M. Ismail College of Medicine, University of Sulaimani, Kurdistan Region, Iraq.
  • Rbaz Jamal Abdul Family of Medicine, Qatae Hospital, Ministry of Health, Musil, Kurdistan Region, Iraq.

DOI:

https://doi.org/10.17656/jsmc.10438

Keywords:

Chronic kidney disease, Predictors, Progression, Risk factors for progression

Abstract

Background
Chronic kidney disease (often underdiagnosed, and its complications often undertreated) is a worldwide public health problem associated with a significant increase in mortality.


Objective
To find out the common causes of chronic kidney disease in Sulaimani to prevent and accurately assess risk factors for target intervention to prevent or slow down the progression.


Patients and Methods
An observational case series study was accomplished on 192 patients with chronic kidney disease in Sulaimani City from September 2018 to March 2019. Following informed consent, a questionnaire collected demographic and clinical details. Laboratory data of the patients were also collected and statistically analyzed.


Results
The majority (58.9%) of the participants were 18-64 years old, 66.7% lived in urban areas, and 66.1% had a low socioeconomic status. The leading causes of chronic kidney disease in children were glomerular diseases (45.4%) and congenital urological malformations (31.8%), while in adults and elderly group, diabetic nephropathy (25.9%), glomerular diseases (19.4%), and hypertension (16.5%) were the most common causes. About 50% of all patients were diagnosed when they reached advanced stages (stage IV, V), and about 90% of patients diagnosed at early stages progressed to advanced stages. Uncontrolled diabetes, proteinuria (≥ 1gm), and uncontrolled blood pressure were significant risk factors for progression.


Conclusion
Chronic kidney disease is underdiagnosed and undertreated in our region. Early detection and measures to slow disease progression should be encouraged.

References

Kefale B, Alebachew M, Tadesse Y, Engidawork E. Quality of life and its predictors among patients with chronic kidney disease: A hospital-based cross-sectional study. PloS one. 2019; 14(2):e0212184.

Barsoum RS. Chronic kidney disease in the developing world. New England Journal of Medicine. 2006; 354(10):997-9.

El Nahas AM, Bello AK. Chronic kidney disease: the global challenge. The Lancet. 2005; 365(9456):331-40.

Levey AS, Eckardt K-U, Tsukamoto Y, Levin A, Coresh J, Rossert J, et al. Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney international. 2005; 67(6):2089-100.

Radhakrishnan J, Remuzzi G, Saran R, Williams DE, Rios-Burrows N, Powe N, et al. Taming the chronic kidney disease epidemic: a global view of surveillance efforts. Kidney international. 2014; 86(2):246-50.

WHO. Global Recommendations on Physical Activity for Health: 18-64 Years Old; WHO: Geneva, Switzerland, 2011. Available from: https://who.int/dietphysicalactivity/factsheet_recommendations/en/

Omer W, Al-Hadithi T. Developing a socioeconomic index for health research in Iraq. East Mediterr Health J. 2017;23(10):670-7.

Chang AR, Loser M, Malhotra R, Appel LJ. Blood pressure goals in patients with CKD: a review of evidence and guidelines. Clinical Journal of the American Society of Nephrology. 2019; 14(1):161-9.

Levey AS, Coresh J, Greene T, Marsh J, Stevens LA, Kusek JW, et al. Expressing the Modification of Diet in Renal Disease Study equation for estimating glomerular filtration rate with standardized serum creatinine values. Clinical chemistry. 2007;53(4):766-72.

Hoste L, Dubourg L, Selistre L, De Souza VC, Ranchin B, Hadj-Aïssa A, et al. A new equation to estimate the glomerular filtration rate in children, adolescents and young adults. Nephrology Dialysis Transplantation. 2014;29(5):1082-91.

Foundation NK. KDOQI clinical practice guideline for diabetes and CKD: 2012 update. American Journal of Kidney Diseases. 2012;60(5):850-86.

Hogg RJ, Furth S, Lemley KV, Portman R, Schwartz GJ, Coresh J, et al. National Kidney Foundation’s Kidney Disease Outcomes Quality Initiative clinical practice guidelines for chronic kidney disease in children and adolescents: evaluation, classification, and stratification.

Pediatrics. 2003; 111(6):1416-21.

Mortazavi F, Rafiee A. Etiology of pediatric chronic kidney diseases in the north-west of Iran. Pakistan Journal of Biological Sciences. 2010; 13(9):456-9.

Safouh H, Fadel F, Essam R, Salah A, Bekhet A. Causes of chronic kidney disease in Egyptian children. Saudi Journal of Kidney Diseases and Transplantation. 2015; 26(4):806.

Ullah K, Butt G, Masroor I, Kanwal K, Kifayat F. Epidemiology of chronic kidney disease in a Pakistani population. Saudi Journal of Kidney Diseases and Transplantation. 2015; 26(6):1307.

Salman M, Khan AH, Adnan AS, Sulaiman SAS, Hussain K, Shehzadi N, et al. Attributable causes of chronic kidney disease in adults: a five-year retrospective study in a tertiary-care hospital northeast of the Malaysian Peninsula. Sao Paulo Medical Journal. 2015;133(6):502-9.

Amoako YA, Laryea DO, Bedu-Addo G, Andoh H, Awuku YA. Clinical and demographic characteristics of chronic kidney disease patients in a tertiary facility in Ghana. Pan Afr Med J. 2014;18:274.

Kang E, Han M, Kim H, Park SK, Lee J, Hyun YY, et al. Baseline general characteristics of the Korean chronic kidney disease: report from the Korean Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD). Journal of Korean Medical Science. 2017; 32(2):221-30.

Published

2023-12-21

How to Cite

1.
Munthir N, Sharif D, Ismail S, Abdul R. PATTERN AND PROGRESSION OF CHRONIC KIDNEY DISEASE IN A GROUP OF PATIENTS IN SULAIMANI CITY. JSMC [Internet]. 2023 Dec. 21 [cited 2024 Jul. 15];13(4):12. Available from: https://jsmc.univsul.edu.iq/index.php/jsmc/article/view/jsmc-10438

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