THE ROLE OF STAGING LAPAROTOMY IN GRADING GYNECOLOGICAL MALIGNANCIES

Authors

  • Soma Tahir Abdulla Sulaimani Maternity Teaching Hospital, Sulaimani, Kurdistan Region, Iraq.
  • Tahir Abdulla Hussein Sulaimani Maternity Teaching Hospital, Sulaimani, Kurdistan Region, Iraq.
  • Maryam Bakir Mahmood Sulaimani Maternity Teaching Hospital, College of Medicine, University of Sulaimani, Kurdistan Region, Iraq.

DOI:

https://doi.org/10.17656/jsmc.10377

Keywords:

Endometrial cancer, Gynecological cancer, Grading, Ovarian cancer, Sulaimani

Abstract

Background 

Staging laparotomy can provide optimal care for gynecological malignancies by avoiding over treatment and under treatment.

Objectives 

The aim was to explore the difference between surgical and clinical disease staging of gynecological malignancies. 

Patients and Methods

A retrospective observational study was performed on 30 women who were operated on for gynecological malignancies and were admitted to the Sulaimani Maternity Teaching Hospital from January 2019 to December 2020. Inclusion criteria included women diagnosed with gynecological malignancies before staging laparotomy. However, exclusion criteria included previous abdominal surgeries for other gynecological malignancies. In addition, demographic features, previous diagnostic methods, and intraoperative staging were recorded.

Results

The mean±SD (standard deviation) age was 51.8±14.9 years (range, 12 to 72), and the majority (56.7%) was between 50-69 years. The mean±SD of patients’ gravida and para were 4.5±3.5 (range, 0-12) and 3.4±2.8 (range, 0-8), respectively. In addition, 20% of women had a personal history (13.3%) of tumors or familial history (6.7%)—most women (50%) presented with abnormal vaginal bleeding, either postmenopausal or menstrual abnormalities. Most women with endometrial tumors (50%) had been afflicted with adenocarcinoma (endometrioid type); however, the most common types of ovarian tumors were granulosa cell tumor, papillary serous adenocarcinoma, and malignant ovarian dysgerminoma in 10%, 10%, and 6.7%, respectively. The association between clinical staging and staging laparotomy was significant. There was a 60% upgrade from a lower stage to a higher stage; however, downgrading was only 3.3%. 

Conclusion

The current study showed a significant association between clinical staging and staging laparotomy of gynecological malignancies.

References

Jemal A, Siegel R, Ward E, Hao Y, Xu J, Murray T, et al. Cancer Statistics, 2008. CA Cancer J Clin. 2008;58(2):71–96. DOI: https://doi.org/10.3322/CA.2007.0010

Ries LAG, Young JL, Keel GE, Eisner MP, Lin YD, Horner MD. Cancer Survival Among Adults: US SEER Program, 1988-2001 Patient and Tumor Characteristics. 2007. 1988–2001 p.

Mining L, Patrono MG, Gallego RA, Bernabé JV De, Diaz-Padilla I. Surgical Treatment of Ovarian Cancer. In: Ovarian Cancer - A Clinical and Translational Update. Madrid: INTECH; 2013. p. 161–82.

Siegel R, Desantis C, Virgo K, Stein K, Mariotto A, Smith T, et al. Cancer Treatment and Survivorship Statistics, 2012. CA CANCER J CLIN. 2012;62(4):220–41. DOI: https://doi.org/10.3322/caac.21149

Bookman MA, Brady MF, Mcguire WP, Harper PG, Alberts DS, Friedlander M. Evaluation of New Platinum-Based Treatment Regimens in Advanced-Stage Ovarian Cancer : A Phase III Trial of the Gynecologic Cancer InterGroup. J Clin Oncol. 2009;27(9):1419–25. DOI: https://doi.org/10.1200/JCO.2008.19.1684

Benedet J, Denny L, Jones HW, Kavanagh J, Kitchener H, Kohorn E, et al. Staging Classifications and Clinical Practice Guidelines for Gynaecological Cancers. In: FIGO Committee on Gynecologic Oncology Guidelines. 2006. p. 1–160.

Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin. 2013;63(1):11–30. DOI: https://doi.org/10.3322/caac.21166

Sonoda Y. Surgical treatment for apparent early-stage endometrial cancer. Obs Gynecol Sci. 2014;57(1):1–10. DOI: https://doi.org/10.5468/ogs.2014.57.1.1

Pecorelli S. Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int J Gynaecol Obs. 2009;105(2):103–4. DOI: https://doi.org/10.1016/j.ijgo.2009.02.012

Bristow RE, Santillan A, Diaz-Montes TP, Gardner GJ, Giuntoli RL, Meisner BC, et al. Centralization of care for patients with advanced-stage ovarian cancer: A cost-effectiveness analysis. Cancer. 2007;109(8):1513–22. DOI: https://doi.org/10.1002/cncr.22561

Engelen MJA, Kos HE, Willemse PHB, Aalders JG, De Vries EGE, Schaapveld M, et al. surgery by consultant gynecologic oncologists improves survival in patients with ovarian carcinoma. Cancer. 2006;106(3):589–98. DOI: https://doi.org/10.1002/cncr.21616

Grabowski JP, Harter P, Buhrmann C, Lorenz D, Hils R, Kommoss S, et al. Re-operation outcome in patients referred to a gynecologic oncology center with presumed ovarian cancer FIGO I-IIIA after the sub-standard initial surgery. Surg Oncol. 2012;21(1):31–5. DOI: https://doi.org/10.1016/j.suronc.2010.08.006

Harter P, Gnauert K, Hils R, Lehmann TG, Fisseler-Eckhoff A, Traut A, et al. Pattern and clinical predictors of lymph node metastases in epithelial ovarian cancer. Int J Gynecol Cancer. 2007;17(6):1238–44. DOI: https://doi.org/10.1111/j.1525-1438.2007.00931.x

Published

2022-12-21

How to Cite

1.
Abdulla S, Hussein T, Mahmood M. THE ROLE OF STAGING LAPAROTOMY IN GRADING GYNECOLOGICAL MALIGNANCIES. JSMC [Internet]. 2022 Dec. 21 [cited 2024 Jul. 13];12(4):339-44. Available from: https://jsmc.univsul.edu.iq/index.php/jsmc/article/view/jsmc-10377

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