ENDOSCOPIC DIAGNOSIS OF SUSPECTED H. PYLORI INFECTION IN SULAIMANI PEDIATRIC TEACHING HOSPITAL

Heersh HMH Raof Saeed a



Department of Pediatrics, College of Medicine, University of Sulaimani, Kurdistan Region, Iraq. 
 
 
Submitted: 5/2/2019; Accepted: 27/6/2019; Published: 21/9/2019

ABSTRACT


Background 

Helicobacter pylori is a common cause for chronic gastritis, gastric atrophy, peptic ulcer disease in the pediatric age group. Infection is more common in developing countries; Transmission is fecal-oral, or oral-oral from human-to-human contact. Serology, stool antigen, urea breath test, and endoscopy are used for diagnosis.


Objectives

To evaluate endoscopic finding and biopsy results of those children who underwent upper gastrointestinal endoscopy 


Patients and Methods

We conducted this study on 49 children, all suspected of H. pylori infection, different methods were used for diagnosis serology, stool antigen and urea breath test. Every child checked by anesthesiologist before endoscopy, in all children endoscopy done after giving anesthesia, biopsy taken from every child and sent to histopathology.


Results

In our study, the sensitivity of serology was 60%, while the sensitivity of stool antigen test for H. pylori was 80% and the sensitivity of Urea breath test was 92%. Ninety percent of children with endoscopic findings of nodular gastritis were H. pylori  positive on biopsy result while 62% of children with gastritis were positive for H. pylori on biopsy result. 


Conclusions

Urea breath test is the most accurate test for diagnosis of H. pylori infection, next test is stool for H. pylori antigen while serology is not accurate for diagnosis.



KEYWORDS

 H. pylori, Urea breath test, Stool antigen, Gastritis.