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jsmc-10048


SEROPREVALENCE OF ANTI-RESPIRATORY SYNCYTIAL VIRUS ANTIBODIES IN HOSPITALIZED PATIENTS WITH ACUTE RESPIRATORY TRACT INFECTIONS IN SULAIMANI GOVERNORATE/ IRAQ


Tariq A. G. Aziz * and Ali Hattem Hussain **


*  Department of Microbiology, School of Medicine, Faculty of Medical Sciences, University of Sulaimani
** Sulaimani Technical College, Sulaimani Polytechnic University.


Submitted: 23/7/2013; Accepted: 20/11/2013


ABSTRACT


Background

Respiratory syncytial virus (RSV) is a major respiratory pathogen among children, and it is a leading cause of bronchiolitis and pneumonia among hospitalized children.

Objectives

To measure the seroprevalence of anti-RSV antibodies among hospitalized children presenting with acute respiratory tract infections in Sulaimani Governorate, Kurdistan/Iraq.

Methods

ELISA technique was used to detect serum anti-RSV antibodies (IgM and IgG antibodies) from 300 hospitalized children less than 5 years old with a diagnosis of acute respiratory tract infections.

Results

IgM anti-RSV was positive in 61 (20.3%) out of 300 children. The highest seroprevalence was found in the age group 1 to < 2 years, while the lowest in the age group 2 to < 3 years. No significant gender difference was found among seropositive children. The IgM anti – RSV seropositive children were suffering from bronchiolitis, pneumonia, or other respiratory tract infections in a frequency of 29 (47.5%), 15 (24.6%), and 17 (27.9%). The IgG anti-RSV antibodies were positive in 216 (72%) out of the 300 children, and there was a gradual increase in percentage of seropositivity with increasing age.

Conclusion

RSV is a common viral respiratory pathogen among hospitalized children in Sulaimani governorate/ Kurdistan/Iraq, and most of the children had experienced RSV infection by the age of five years.

KEYWORDS

Respiratory syncytial virus, hospitalized children, Sulaimani Governorate, ELISA technique.