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Case Report


Shanaz Mohammad Gaphor * and Mustafa Jamel Abdullah **

*   Oral Medicine Clinic, School of Dentistry, University of Sulaimani.
** Oral Medicine Clinic, school of dentistry, University of Sulaimani.

Submitted: 17/7/2012; Accepted: 8/2/2013Published 1/6/2013


The gingiva is a target of autoimmune diseases and about 10% of patients with oral lichen planus have the disease confined to the gingiva, clinically named desquamative gingivitis. The purpose of this paper is to describe 59 year-old female with atrophic-erosive gingival lichen planus that was presented to the Department of Oral Diagnosis, School of Dentistry at Sulaimani University service for evaluation of persistent pain, associated soreness and burning of her gingiva for 3-4 years, which were localized for anterior maxillary region. The histopathological examination confirmed the diagnosis of atrophic-erosive oral lichen planus. The treatment prescribed for the patient was topical and systemic corticosteroid (prednisolone). Substantial improvement was observed in the gingival lesion with reduction in erythema in some regions and complete resolution of pain. The results presented allow the authors to consider the association between local and systemic corticosteroid as a potential therapy for atrophic-erosive gingival lichen planus.


Lichen planus, Corticosteroid, Prednisolone.


1. Agahahosseini F, Arbabi-Kalati F, Fashtami L, Fateh M, Djavid GE. Treatment of oral lichen planus with photodynamic therapy mediated methylene blue: a case report. Med Oral Patol Oral Cir Bucal 2006; 1:26–9.

2. Scully C, Carozzo M. Oral mucosal disease: lichen planus. Br J Oral Maxillofac Surg. 2008; 46:15–21.

3-Nagao T, Ikeda N, Fukano H, Hashimoto S, Shimozato K, Warnakulasuriya S. Incidence rates for oral leukoplakia and lichen planus in a Japanese population. J Oral Pathol Med  2005; 34:532-9.

4-van der Waal I. Oral lichen planus and oral lichenoid lesions; a critical appraisal with emphasis on the diagnostic aspects. Med Oral Patol Oral Cir Bucal. 2009; 14 (7):E310-4.

5-Pindborg JJ, Reichart PA, Smith CJ, Van der Waal I. Histological typing of cancer and precancer of the oral mucosa. 2nd ed. Springer, New York, 1997; 30.

6-Andreasen JO Oral lichen planus .A clinical evaluation of 115 cases. Oral Surg Oral Med Oral Pathol. 1968;  25: 31-42. 

7- Holmstrup P, Schiotz AW, Westergaard J.  Effect of dental plaque control on gingival lichen planus. Oral Surg Oral Med Oral Pathol 1990; 69:585–90.

8-Mignona MD, Lo RL, Fedele S. Gingival involvement of oral lichen planus in a series of 700 patients. J Clin Periodontol 2005; 32:1029-1033.

9- Ismail SB, Kumar SKS, Zain RB. Oral lichen planus and lichenoid reactions: etiopathogenesis, diagnosis, management, and malignant transformation. J Oral Sci. 2007; 49:89–106.

10-Scully C, Beyli M, Ferreiro MC, Ficarra G, Gill Y, Griffiths M, Holmstrup P, Mutlu S, Wray D. Update on oral lichen planus: etiopathogenesis and management. Crit Rev Oral Biol Med . 1998 ; 9: 86-122. 

11-Scully C, Eisen D, Carrozzo M. Management of oral lichen planus. Am J Clin Dermatol. 2000; 1: 287-306.

12-Eisen D. The clinical features, malignant potential, and systemic association of oral lichen planus: a study of 723 patients. J Am Acad Dermatol. 2002; 46: 207-214.

13-Voute AB, Schulten EA, Langendijk PN, Nieboer C, van der Wall I. Cyclosporin A in an adhesive base for treatment of recalcitrant oral lichen planus. An open trial. Oral Surg Oral Med Oral Pathol. 1994; 78: 437-441. 

14-Xue JL, Fan MW, Wang SZ, Chen XM, Li Y, Wang L. Aclinical study of 674 patients with oral lichen planus in China. J Oral Pathol Med. 2005; 34: 467-472.

15-Carbone M, Goss E, Carrozo M, Castellano S, Conrotto D, Broccoletti R et al. Systemic and topical corticosteroid treatment of oral lichen planus: a comparative study with long term follow-up. J Oral Pathol Med. 2003; 2:323–9.

16-Thongprasom K, Dhanuthai K. Steriods in the treatment of lichen planus: a review.J Oral Sci. 2008; 50(4):377-85.

17-Czock D, Keller F, Rasche FM, Häussler U. Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids. Clin Pharmacokinet.  2005; 44:61-98. 

18- Al-Hashimi I, Schifter M, Lockhart PB, Wray D, Brennan M, Migliorati CA, et al. Oral lichen planus and oral lichenoid lesions: diagnostic and therapeutic considerations. Oral surgery, oral medicine, oral 
pathology, oral radiology, and endodontics. 2007;103 Suppl:S25 e1-12.