PREVALENCE OF LOW FREE TESTOSTERONE LEVEL IN MEN WITH TYPE 2 DIABETES MELLITUS


Taha Othman Mahwi a, and Soran Khalil Hassan b 



a  Department of Medicine, College of Medicine, University of Sulaimani, Kurdistan Region, Iraq. 
b  Iraqi Board Candidate of Internal Medicine, Sulaimani, Kurdistan Region, Iraq.
 

Submitted: 16/12/2021; Accepted: 10/6/2022; Published: 21/9/2022



ABSTRACT 


Background 

Prevalence of low serum free testosterone levels in men with type2 diabetes mellitus has been reported worldwide.


Objectives 

To find the prevalence of low free testosterone levels in type2 diabetic men.


Patients and Methods

A cross-sectional study was carried out in (the Diabetic and Endocrine Center) in Sulaimani from the 5th of April, 2017, to the 3rd of January, 2018. Eighty-eight male patients of type two diabetes mellitus who attended the centre for regular follow-up are included. After taking consent and history from the patient, a questionnaire was taken on Sociodemographic data and diabetic characteristics (duration &type of treatment), body mass index, and statin use. In addition, blood tests, including; free testosterone, were measured from morning samples using the ELISA kit (bioactive diagnostic, free testosterone ELISA kit), blood sugar (fasting), HbA1c, serum cholesterol, and serum triglyceride were done for all patients.


Results

There was little relation (correlation coefficient =0.07) (p-value 0.49) between free testosterone and HbA1c% concentration, and serum HbA1c% does not seem to contribute significantly to the free testosterone level variation. Duration of diabetes does not affect free testosterone levels. 


Conclusion

The level of free testosterone in type2 diabetic men was average; there was no correlation between serum HbA1c concentration and serum-free testosterone.



KEYWORDS

Type2 diabetes mellitus, Serum-free testosterone level.