PREVALENCE AND EFFECT OF IRON DEFICIENCY ANEMIA IN CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Kosar Mohamed Ali a and Blnd Ahmad Aziz b



College of Medicine, University of Sulaimani, Kurdistan Region, Iraq. 
b General Internal Medical hospital, Sulaimani, Kurdistan Region, Iraq.


Submitted: 12/7/2019; Accepted: 27/7/2020; Published: 21/9/2020

ABSTRACT


Background 

Anemia is progressively recognized as significant comorbidity in the context of chronic obstructive pulmonary disease (COPD). 


Objectives 

To determine the extent of iron deficiency anemia in both exacerbation of COPD and stable COPD.


Patients and Methods

A prospective, multicenter, cross-sectional study was conducted between April 2017 and January 2018. Two groups of patients were enrolled, group A included those patients admitted in the emergency rooms for the management of acute exacerbation of COPD and group B comprised of those patients with stable COPD visited the consultatory medical department. Inclusion criteria included those patients known cases of COPD and categorized according to the GOLD criteria. 


Results

The study included 150 patients. Group A contained 100 patients. Seventy-nine (79%) were male with a mean age and standard deviation of 66.77 years ± 12.07 years. While the other groups (group B) comprised of 50 patients, 39 (78%) were male with a mean age of 59.86 years ± 9.87 years. The inflammatory marker was significantly more positive in group A (89, 89%) compared to group B (6, 12%), P-value 0.0001. Overall, the low iron profile was found in 15 (15%) patients in group A, and in 2 (4%) patients in group B (P-value 0.0559). Both iron and non-iron deficiency anemia were more prevalent among the exacerbation group (group A).


Conclusion

Anemia is a relatively common finding among COPD patients (both IDA and non-IDA). It is more prevalent among those patients developing frequent exacerbations.  



KEYWORDS

Iron deficiency anemia; COPD; Exacerbation COPD; Chronic obstructive pulmonary disease.